Our experience matches that of Idahocountryboy. For our ranch trucks including the two Dodge Rams that I use pulling our 39 ft Monty, the best MPG is when the Cummins engine is kept at 1800 to 2000 RPM. With this RPM your actual vehicle speed will be determined by Axle Ratio, etc.
I hesitate to actually give MPG figures on any website since some doubt my truthfulness when I tell what ours really is for any trip. I have had some say our figure cannot be true. But, I will take chance here since I really don't care what anyone says when I now the truth.
Just two weeks ago my wife and I traveled to and from Colorado to Southern California, via Colorado US 40, Colorado Hwy 13, I-70, I-15, both ways. We averaged 19.2 MPG with our Ram D3500 Diesel pulling our Monty. We were in Orange Count, LA area two days driving unhooked from the Monty with about 150 miles of city driving, included in the total MPG figure.
This trip was typical with some variations on different times and trips due to weather, fuel quality, (Bio Diesel always drops our MPG by 2 or 3 MPG), etc., but is what we expect. I do use Diesel Kleen added to the fuel in the Summer, Spring and Fall times and Diesel Fuel Supplement added in the Winter months, both sold by Power Service Product Company. We use these products in all of our diesel engines, trucks and ranch equipment.